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Merge pull request #236 from deeptools/FAQ
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added faq with HiCMatrix 12 to 13
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joachimwolff authored May 20, 2020
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15 changes: 15 additions & 0 deletions docs/content/faq.rst
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FAQ
===

.. contents::
:local:

Why the scale of my Hi-C plot suddenly changed
----------------------------------------------
pyGenomeTracks is using `HiCMatrix <https://github.com/deeptools/HiCMatrix>`_ to read the matrix from ``h5`` and ``cool`` format.
From version 12 to version 13, a normalization step when reading ``cool`` file was removed. This normalization was mostly used
when you were providing ``cool`` file from `cooler balance <https://cooler.readthedocs.io/en/latest/cli.html#cooler-balance>`_.

If you want to keep the old scale you need to downgrade to HiCMatrix version 12 but version 13 also correct some bugs so we advice
to change your ``max_value`` in your parameter file to adjust to the new scale.

2 changes: 1 addition & 1 deletion docs/index.rst
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content/possible-parameters
content/adding-new-tracks
content/releases

content/faq

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