This repository contains code that reproduces the main analyses of the following study:

Dimitrios - Georgios Kontopoulos, Ilias Patmanidis, Timothy G. Barraclough, and Samraat Pawar: Higher temperatures amplify the negative effects of mutations on protein stability. 2020. [Submitted]

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Dependencies

• R, version 3.4.4
• MCMCglmm, version 2.26
• MuMIn, version 1.42.1

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Execution

Each script can be run from the command line or from within R using the source command. Any files that are needed for execution (i.e., the phylogeny or a dataset) should be placed in the current working directory.