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The Shannon-Bers model is an integrated mathematical model of cardiac excitation-contraction coupling in the rabbit ventricular myocyte, focusing on detailed Ca handling with four compartments of junctional cleft, subsarcolemmal space, cytosolic bulk, and sarcoplasmic reticulum.

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Matlab code of the Shannon-Bers rabbit ventricular model.

This model is an integrated mathematical model of cardiac excitation-contraction coupling
in the rabbit ventricular myocyte, focusing on detailed Ca handling with four compartments
of junctional cleft, subsarcolemmal space, cytosolic bulk, and sarcoplasmic reticulum.

Reference:
Thomas R. Shannon, Fei Wang, Jose Puglisi, Christopher Weber, Donald M. Bers
"A Mathematical Treatment of Integrated Ca Dynamics Within the Ventricular Myocyte",
Biophys J. 2004 Nov;87(5):3351-71.
doi: https://doi.org/10.1529/biophysj.104.047449

[Erratum in Biophys J. 2012 Apr 18;102(8):1996-2001.]

Please cite the above paper when using this model.

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The Shannon-Bers model is an integrated mathematical model of cardiac excitation-contraction coupling in the rabbit ventricular myocyte, focusing on detailed Ca handling with four compartments of junctional cleft, subsarcolemmal space, cytosolic bulk, and sarcoplasmic reticulum.

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