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exercises/practice/protein-translation/.docs/instructions.md
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# Instructions | ||
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Translate RNA sequences into proteins. | ||
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RNA can be broken into three nucleotide sequences called codons, and then translated to a polypeptide like so: | ||
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RNA: `"AUGUUUUCU"` => translates to | ||
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Codons: `"AUG", "UUU", "UCU"` | ||
=> which become a polypeptide with the following sequence => | ||
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Protein: `"Methionine", "Phenylalanine", "Serine"` | ||
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There are 64 codons which in turn correspond to 20 amino acids; however, all of the codon sequences and resulting amino acids are not important in this exercise. | ||
If it works for one codon, the program should work for all of them. | ||
However, feel free to expand the list in the test suite to include them all. | ||
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There are also three terminating codons (also known as 'STOP' codons); if any of these codons are encountered (by the ribosome), all translation ends and the protein is terminated. | ||
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All subsequent codons after are ignored, like this: | ||
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RNA: `"AUGUUUUCUUAAAUG"` => | ||
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Codons: `"AUG", "UUU", "UCU", "UAA", "AUG"` => | ||
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Protein: `"Methionine", "Phenylalanine", "Serine"` | ||
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Note the stop codon `"UAA"` terminates the translation and the final methionine is not translated into the protein sequence. | ||
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Below are the codons and resulting Amino Acids needed for the exercise. | ||
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| Codon | Protein | | ||
| :----------------- | :------------ | | ||
| AUG | Methionine | | ||
| UUU, UUC | Phenylalanine | | ||
| UUA, UUG | Leucine | | ||
| UCU, UCC, UCA, UCG | Serine | | ||
| UAU, UAC | Tyrosine | | ||
| UGU, UGC | Cysteine | | ||
| UGG | Tryptophan | | ||
| UAA, UAG, UGA | STOP | | ||
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Learn more about [protein translation on Wikipedia][protein-translation]. | ||
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[protein-translation]: https://en.wikipedia.org/wiki/Translation_(biology) |
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{ | ||
"authors": [ | ||
"pfertyk" | ||
], | ||
"files": { | ||
"solution": [ | ||
"protein_translation.gd" | ||
], | ||
"test": [ | ||
"protein_translation_test.gd" | ||
], | ||
"example": [ | ||
".meta/example.gd" | ||
] | ||
}, | ||
"blurb": "Translate RNA sequences into proteins.", | ||
"source": "Tyler Long" | ||
} |
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const CODON_TO_PROTEINE = { | ||
'AUG': 'Methionine', | ||
'UUU': 'Phenylalanine', | ||
'UUC': 'Phenylalanine', | ||
'UUA': 'Leucine', | ||
'UUG': 'Leucine', | ||
'UCU': 'Serine', | ||
'UCC': 'Serine', | ||
'UCA': 'Serine', | ||
'UCG': 'Serine', | ||
'UAU': 'Tyrosine', | ||
'UAC': 'Tyrosine', | ||
'UGU': 'Cysteine', | ||
'UGC': 'Cysteine', | ||
'UGG': 'Tryptophan', | ||
'UAA': 'STOP', | ||
'UAG': 'STOP', | ||
'UGA': 'STOP' | ||
} | ||
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func proteins(strand): | ||
var protein_list = [] | ||
for i in range(0, len(strand), 3): | ||
var codon = strand.substr(i, 3) | ||
var proteine = CODON_TO_PROTEINE[codon] | ||
if proteine == 'STOP': | ||
break | ||
protein_list.append(proteine) | ||
return protein_list |
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exercises/practice/protein-translation/.meta/tests.toml
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# This is an auto-generated file. | ||
# | ||
# Regenerating this file via `configlet sync` will: | ||
# - Recreate every `description` key/value pair | ||
# - Recreate every `reimplements` key/value pair, where they exist in problem-specifications | ||
# - Remove any `include = true` key/value pair (an omitted `include` key implies inclusion) | ||
# - Preserve any other key/value pair | ||
# | ||
# As user-added comments (using the # character) will be removed when this file | ||
# is regenerated, comments can be added via a `comment` key. | ||
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[2c44f7bf-ba20-43f7-a3bf-f2219c0c3f98] | ||
description = "Empty RNA sequence results in no proteins" | ||
include = false | ||
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[96d3d44f-34a2-4db4-84cd-fff523e069be] | ||
description = "Methionine RNA sequence" | ||
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[1b4c56d8-d69f-44eb-be0e-7b17546143d9] | ||
description = "Phenylalanine RNA sequence 1" | ||
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[81b53646-bd57-4732-b2cb-6b1880e36d11] | ||
description = "Phenylalanine RNA sequence 2" | ||
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[42f69d4f-19d2-4d2c-a8b0-f0ae9ee1b6b4] | ||
description = "Leucine RNA sequence 1" | ||
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[ac5edadd-08ed-40a3-b2b9-d82bb50424c4] | ||
description = "Leucine RNA sequence 2" | ||
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[8bc36e22-f984-44c3-9f6b-ee5d4e73f120] | ||
description = "Serine RNA sequence 1" | ||
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[5c3fa5da-4268-44e5-9f4b-f016ccf90131] | ||
description = "Serine RNA sequence 2" | ||
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[00579891-b594-42b4-96dc-7ff8bf519606] | ||
description = "Serine RNA sequence 3" | ||
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[08c61c3b-fa34-4950-8c4a-133945570ef6] | ||
description = "Serine RNA sequence 4" | ||
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[54e1e7d8-63c0-456d-91d2-062c72f8eef5] | ||
description = "Tyrosine RNA sequence 1" | ||
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[47bcfba2-9d72-46ad-bbce-22f7666b7eb1] | ||
description = "Tyrosine RNA sequence 2" | ||
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[3a691829-fe72-43a7-8c8e-1bd083163f72] | ||
description = "Cysteine RNA sequence 1" | ||
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[1b6f8a26-ca2f-43b8-8262-3ee446021767] | ||
description = "Cysteine RNA sequence 2" | ||
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[1e91c1eb-02c0-48a0-9e35-168ad0cb5f39] | ||
description = "Tryptophan RNA sequence" | ||
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[e547af0b-aeab-49c7-9f13-801773a73557] | ||
description = "STOP codon RNA sequence 1" | ||
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[67640947-ff02-4f23-a2ef-816f8a2ba72e] | ||
description = "STOP codon RNA sequence 2" | ||
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[9c2ad527-ebc9-4ace-808b-2b6447cb54cb] | ||
description = "STOP codon RNA sequence 3" | ||
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[f4d9d8ee-00a8-47bf-a1e3-1641d4428e54] | ||
description = "Sequence of two protein codons translates into proteins" | ||
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[dd22eef3-b4f1-4ad6-bb0b-27093c090a9d] | ||
description = "Sequence of two different protein codons translates into proteins" | ||
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[d0f295df-fb70-425c-946c-ec2ec185388e] | ||
description = "Translate RNA strand into correct protein list" | ||
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[e30e8505-97ec-4e5f-a73e-5726a1faa1f4] | ||
description = "Translation stops if STOP codon at beginning of sequence" | ||
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[5358a20b-6f4c-4893-bce4-f929001710f3] | ||
description = "Translation stops if STOP codon at end of two-codon sequence" | ||
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[ba16703a-1a55-482f-bb07-b21eef5093a3] | ||
description = "Translation stops if STOP codon at end of three-codon sequence" | ||
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[4089bb5a-d5b4-4e71-b79e-b8d1f14a2911] | ||
description = "Translation stops if STOP codon in middle of three-codon sequence" | ||
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[2c2a2a60-401f-4a80-b977-e0715b23b93d] | ||
description = "Translation stops if STOP codon in middle of six-codon sequence" | ||
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[1e75ea2a-f907-4994-ae5c-118632a1cb0f] | ||
description = "Non-existing codon can't translate" | ||
include = false | ||
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[9eac93f3-627a-4c90-8653-6d0a0595bc6f] | ||
description = "Unknown amino acids, not part of a codon, can't translate" | ||
include = false | ||
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[9d73899f-e68e-4291-b1e2-7bf87c00f024] | ||
description = "Incomplete RNA sequence can't translate" | ||
include = false | ||
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[43945cf7-9968-402d-ab9f-b8a28750b050] | ||
description = "Incomplete RNA sequence can translate if valid until a STOP codon" | ||
include = false |
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exercises/practice/protein-translation/protein_translation.gd
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func proteins(strand): | ||
pass |
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exercises/practice/protein-translation/protein_translation_test.gd
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func test_methionine_rna_sequence(solution_script): | ||
var value = "AUG" | ||
var expected = ["Methionine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_phenylalanine_rna_sequence_1(solution_script): | ||
var value = "UUU" | ||
var expected = ["Phenylalanine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_phenylalanine_rna_sequence_2(solution_script): | ||
var value = "UUC" | ||
var expected = ["Phenylalanine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_leucine_rna_sequence_1(solution_script): | ||
var value = "UUA" | ||
var expected = ["Leucine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_leucine_rna_sequence_2(solution_script): | ||
var value = "UUG" | ||
var expected = ["Leucine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_serine_rna_sequence_1(solution_script): | ||
var value = "UCU" | ||
var expected = ["Serine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_serine_rna_sequence_2(solution_script): | ||
var value = "UCC" | ||
var expected = ["Serine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_serine_rna_sequence_3(solution_script): | ||
var value = "UCA" | ||
var expected = ["Serine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_serine_rna_sequence_4(solution_script): | ||
var value = "UCG" | ||
var expected = ["Serine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_tyrosine_rna_sequence_1(solution_script): | ||
var value = "UAU" | ||
var expected = ["Tyrosine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_tyrosine_rna_sequence_2(solution_script): | ||
var value = "UAC" | ||
var expected = ["Tyrosine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_cysteine_rna_sequence_1(solution_script): | ||
var value = "UGU" | ||
var expected = ["Cysteine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_cysteine_rna_sequence_2(solution_script): | ||
var value = "UGC" | ||
var expected = ["Cysteine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_tryptophan_rna_sequence(solution_script): | ||
var value = "UGG" | ||
var expected = ["Tryptophan"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_stop_codon_rna_sequence_1(solution_script): | ||
var value = "UAA" | ||
var expected = [] | ||
return [solution_script.proteins(value), expected] | ||
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func test_stop_codon_rna_sequence_2(solution_script): | ||
var value = "UAG" | ||
var expected = [] | ||
return [solution_script.proteins(value), expected] | ||
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func test_stop_codon_rna_sequence_3(solution_script): | ||
var value = "UGA" | ||
var expected = [] | ||
return [solution_script.proteins(value), expected] | ||
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func test_sequence_of_two_protein_codons_translates_into_proteins(solution_script): | ||
var value = "UUUUUU" | ||
var expected = ["Phenylalanine", "Phenylalanine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_sequence_of_two_different_protein_codons_translates_into_proteins(solution_script): | ||
var value = "UUAUUG" | ||
var expected = ["Leucine", "Leucine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_translate_rna_strand_into_correct_protein_list(solution_script): | ||
var value = "AUGUUUUGG" | ||
var expected = ["Methionine", "Phenylalanine", "Tryptophan"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_translation_stops_if_stop_codon_at_beginning_of_sequence(solution_script): | ||
var value = "UAGUGG" | ||
var expected = [] | ||
return [solution_script.proteins(value), expected] | ||
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func test_translation_stops_if_stop_codon_at_end_of_two_codon_sequence(solution_script): | ||
var value = "UGGUAG" | ||
var expected = ["Tryptophan"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_translation_stops_if_stop_codon_at_end_of_three_codon_sequence(solution_script): | ||
var value = "AUGUUUUAA" | ||
var expected = ["Methionine", "Phenylalanine"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_translation_stops_if_stop_codon_in_middle_of_three_codon_sequence(solution_script): | ||
var value = "UGGUAGUGG" | ||
var expected = ["Tryptophan"] | ||
return [solution_script.proteins(value), expected] | ||
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func test_translation_stops_if_stop_codon_in_middle_of_six_codon_sequence(solution_script): | ||
var value = "UGGUGUUAUUAAUGGUUU" | ||
var expected = ["Tryptophan", "Cysteine", "Tyrosine"] | ||
return [solution_script.proteins(value), expected] | ||
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