v2.5.3

Full Changelog: v2.5.2...v2.5.3

v2.5.2

Sniffles requires python to be==3.10.15 given a constrain of edlib (py)

v2.5

What's Changed

• Improved detection of large Deletion and Duplication SVs (>50kb) by manteiners
• Improved implementation of combine for large datasets by manteiners
• fix parallelism for OSX/MacOS by @yfarjoun in #499
• Optionally emit SV lengths by @yfarjoun in #504
• Update vcf.py to have correct END value for DEL SVTYPE by @gaberudy in #519
• Add check for empty list by @bbimber in #521

Full Changelog: v2.4...v2.5

v2.4

Full Changelog: v2.3.3...v2.4

v2.3.3

Bugfixes to make sure sniffles shuts down properly.

Full Changelog: v2.3.2...v2.3.3

v2.3.2

manage the Sniffles2Exit exception in order to not have --version and --help trowing an exit code 1 which made conda not accept sniffles v2.3.1

Full Changelog: v2.3.1...v2.3.2

Sniffles v2.3.1

Bug fixes that prevented pip installation to work and thus conda was unable to build and release
Full Changelog: v2.3...v2.3.1

Sniffles v2.3

This release includes new features for multisample calling and some restructuring of the codebase to facilitate easier development in the future.

New features:

• Multisample calling for large input sets
  Sniffles multiprocessing code has undergone a major rewrite with focus of enabling multisample calling for a large number of input files. To support this, the new optional dependency psutil can be installed along with sniffles.

• Using alignments for multisample calling
  Alignments can be used to improve separation of variants in multisample calling. This uses the new optional dependency edlib and can be tweaked with the new argument --combine-pctseq defaulting to 0.7.

Required Python version has been updated to Python 3.10.

Sniffles v2.2

This release includes a number of updated implementation, bug fixes and usability improvements.

• Low frequency SV caller mode --non-germline has been updated to --mosaic
• Sniffles now allow SV on the same breakpoint
• Minimum SV length is updated to 50 bases
• Minimum mapping quality is set to 20 as default
• Translocation events: require a minimum anchor on each chromosome of 1kb and there a strand check (--bnd-min-split-length and --qc-bnd-filter-strand)
• We include a link to a Sniffles2 plotting tools: https://github.com/farhangus/sniffle2_plot

Sniffles v2.0.7

This release includes a number of minor bugfixes and usability improvements.

• Create output directories if they are not existing yet (@wdecoster)
• Change --max-splits-kb to float (@wdecoster)
• Fixed a problem where exit code 0 was returned on errors