Myelinated Axon Model

Modeling the effect of intra-axonal heterogeneity on the action potential conduction

Getting Started

Prerequisites

To run the model you will need MATLAB. This model and the associated GUI have been tried using the following combinations:

• MATLAB R2013b running on Windows 7
• MATLAB R2016a running on OSX El Capitan

Installing

Clone or copy the directory to any location. Add the directory to the MATLAB path, or, at the MATLAB command prompt run:

>>Setup()

which will add the directory to the user's MATLAB path (after asking) and open the GUI.

Reproducing the data

For exact data reproduction, use MATLAB 2021b.

In order to replicate the values of the Research Project 2, Group 2B run:

>>RunModel.m 			% voltage traces data for variation model
>>makeFigures		 	% recreate all figures used in the report

which are in the main directory. There is more example code in the Examples directory which will replicate other uses of the model (in Bakiri et al. (2011), Ford et al. (2015)) and Arancibia-Carcamo et al. (2017).

Authors

• Max Jacobs
• Jarno Koetsier
• Giorgia Del Missier
• Xenia Sterl

Research project 2

Master of Systems Biology

Maastricht University