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Minimap2-2.27 (r1193)

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@lh3 lh3 released this 12 Mar 17:20
· 28 commits to master since this release

Notable changes to minimap2:

  • New feature: added the lr:hq preset for accurate long reads at ~1% error
    rate. This was suggested by Oxford Nanopore developers (#1127). Whether
    this preset works well for PacBio HiFi reads has not been tested.

  • New feature: added the map-iclr preset for Illumina Complete Long Reads
    (#1069), provided by Illumina developers.

  • New feature: added option -b to specify mismatch penalty for base
    transitions (i.e. A-to-G or C-to-T changes).

  • New feature: added option --ds to generate a new ds:Z tag that
    indicates uncertainty in INDEL positions. It is an extension to cs. The
    mgutils-es6.js script in minigraph parses ds.

  • Bugfix: avoided a NULL pointer dereference (#1154). This would not have an
    effect on most systems but would still be good to fix.

  • Bugfix: reverted the value of ms:i to pre-2.22 versions (#1146). This was
    an oversight. See fcd4df2 for details.

Notable changes to paftools.js and mappy:

  • New feature: expose bw_long to mappy's Aligner class (#1124).

  • Bugfix: fixed several compatibility issues with k8 v1.0 (#1161 and #1166).
    Subcommands "call", "pbsim2fq" and "mason2fq" were not working with v1.0.

Minimap2 should output identical alignments to v2.26, except the ms tag.

(2.27: 12 March 2024, r1193)