periodontitis

This code was created using BioMASS version 0.5.2. For the latest version of BioMASS, please refer to the following site https://github.com/biomass-dev/biomass

BioMASS version 0.5.2 is included in this repository. So, after obtaining this repository,

pip install -r requirements.txt

to install the necessary files.

parameter_estimation.py

Code for parameter estimation However, the file registered in the repository already contains the estimated parameter file.

periodontitis.py

Run periodontal disease model with estimated parameters

CCL2_KO.py

Knockout simulation of CCL2

RANKL_KO_vs_OE.py

Comparison of knockout and overexpression conditions of RANKL