v0.6

• Deprecated 1000G/NHLBI-based putative germline filter and transitioned to ExAC-based filtering
• Use a bedtools-based method to annotate trinucleotide context in MAF
• Cleaned up code and consolidated static files into a single Rdata object for ease of use
• Included a test MAF (TCGA UCEC) as an example input MAF
• By default will use homopolymer QC filter but can be explicitly turned off
  • All other filters are off by default

publication code

This is the code used for generating the hotspots from doi:10.1038/nbt.3391