The bacterial Genome Alignment Service uses progressiveMauve to produce a whole genome alignment of two or more genomes. The resulting alignment can be visualized within the BV-BRC website, providing insight into homologous regions and changes due to DNA recombination. It should be noted that this service is currently released as beta. As always, we appreciate your feedback.
This module is a component of the BV-BRC build system. It is designed to fit into the
dev_container infrastructure which manages development and production deployment of
the components of the BV-BRC. More documentation is available here.
There is one application service specification defined here:
- GenomeAlignment: Service that that provides the backend for the BV-BRC web inerface; it takes genomes as input.
The code in this module provides the BV-BRC application service wrapper scripts for the genome annotation service as well as some backend utilities:
| Script name | Purpose |
|---|---|
| App-GenomeAlignment.pl | App script for the Genome Alignment Service |
Darling, A.E., B. Mau, and N.T. Perna, progressiveMauve: multiple genome alignment with gene gain, loss and rearrangement. PloS one, 2010. 5(6): p. e11147.