Source code and data for "Causal reasoning over knowledge graphs leveraging drug-perturbed and disease-specific transcriptomic signatures for drug discovery"

Elucidate and visualise a compound's mechanism of action by combining structure-based target prediction with gene expression-based causal reasoning, plus pathway enrichment to put results into biological context. GUI-based (minimal coding experience required).

Application of the Simple Sum method for testing co-localization of GWAS with any other SNP-level data (e.g. eQTL data)

Software to classify biological phenotypes from single-cell image-based morphology profiles

PK/PD framework to assess the pharmacological properties of Islatravir (ISL)

Multilabel classification using pytorch neuralnetwork, optimized hyperparameter using optuna.

Fall 2022 Bioengineering 298 Final Project: using protein networks to understand drug and disease mechanisms

Physiological modeling into the metaverse of Mycobacterium tuberculosis beta CA inhibition mechanism