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[Platform]: Comparative genomics visualisation #516

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merged 62 commits into from
Nov 27, 2024
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@carcruz carcruz commented Nov 1, 2024

[Platform]: Comparative genomics visualisation

Description

Issue: opentargets/issues#3366
Deploy preview: (link)

Todo:

  • Styles
  • Legend text size
  • Rename species - Fruit fly, Nematode
  • Interaction
  • Tooltip on each dot with legend
  • Hover on Species highlights only specie's dots
  • Export image
  • Downloads data
  • Highlight chart rows based on prop (CHART_VIEW_MODE)

Highlight assessment
Default - Paralogues - Mouse ortholog identity

Type of change

  • New feature (non-breaking change which adds functionality)

How Has This Been Tested?

Please check the section where it is displayed

  • Check the comparative genomics section on the target profile
  • Check Tissue specificity in target prioritisation
  • Check Mouse ortholog identity in target prioritisation

Checklist:

  • I have commented my code, particularly in hard-to-understand areas
  • My changes generate no new warnings
  • I have made corresponding changes to the documentation

carcruz and others added 30 commits July 22, 2024 22:19
* [Platform] Add Profile and ProfileHeader to variant page (#376)

* [Platform]: variant page widgets init (#380)

* draft pharmacokinetics widget (#383)

* move reported protein link to description (#381)

* [Platform] Add GWAS credible sets widget to variant page (#390)

* [Platform] Add QTL credible sets widget to variant page (#396)

* [Platform] Add Uniprot id to Uniprot description link (#401)

* [Platform] Add allele frequency plot to variant page metadata section (#403)

* frequency vis examples

* polish plots

* allele frequency bars

* use flex for allele frequency plot

* do not import grid

* [Platform] Clean up variant page sections and summaries (#404)

* [Platform] Update variant page QTL credible sets widget (#406)

* [Platform] Use API for variant page header (#412)

* [Platform] Correct dbXref link in variant page header (#414)

* [Platform] Fix clinvar dbXref (#417)

* [Platform] Use API for metadata in variant page (#420)
* [Platform] Add Profile and ProfileHeader to variant page (#376)

* [Platform]: variant page widgets init (#380)

* draft pharmacokinetics widget (#383)

* move reported protein link to description (#381)

* [Platform] Add GWAS credible sets widget to variant page (#390)

* [Platform] Add QTL credible sets widget to variant page (#396)

* [Platform] Add Uniprot id to Uniprot description link (#401)

* [Platform] Add allele frequency plot to variant page metadata section (#403)

* [Platform] Clean up variant page sections and summaries (#404)

* [Platform] Update variant page QTL credible sets widget (#406)

* [Platform] Use API for variant page header (#412)

* [Platform] Correct dbXref link in variant page header (#414)

* [Platform] Fix clinvar dbXref (#417)

* [Platform] Use API for metadata in variant page (#420)

* [Platform] Use API data for in silico predictors widget on variant page (#424)


Co-authored-by: Carlos Cruz <me@carcruzcast.com>

* [Platform] Minor improvements to variant page insilico predictors widget (#429)

* [Platform] Add VEP widget to variant page (#428)
* shorten variant ids in widget descriptions

* avoid DOM nesting warnings
Co-authored-by: Carlos Cruz <me@carcruzcast.com>
* add study table to study page

* fix queries and fill in body

* finish body

* finish draft

* column heading

* link and column updates
* adapt allele frequency plot to order of magnitude

* increase fixed width of right plot column
gjmcn and others added 23 commits October 7, 2024 11:28
* add credible set page

* header and profile

* finish metadata draft

* finish metadata

* consistent case in metadata

* header title and metadata tooltips

* precision

* precsion to 3sf
* sort by exponent then mantissa

* coloc fix
* fix: SharedTraitStudies

* fix: study GWASCredibleSets

* fix: study QTLCredibleSetsSection

---------

Co-authored-by: Carlos Cruz <me@carcruzcast.com>
Base automatically changed from genetics to main November 6, 2024 15:58
@carcruz carcruz merged commit a59a925 into main Nov 27, 2024
11 checks passed
@carcruz carcruz deleted the hc-comparative-genomics branch November 27, 2024 09:49
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4 participants