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New biomass #174

Merged
merged 14 commits into from
Nov 16, 2018
Merged

New biomass #174

merged 14 commits into from
Nov 16, 2018

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feiranl
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@feiranl feiranl commented Nov 1, 2018

Main improvements in this PR:

  • Address issue feat: biomass pseudo-reaction requirements #107, continued with discussion in Fix/biomass composition #159.
  • Update the model biomass to include cofactors and ions
  • Cofactors and ions composition were taken from several reference and YMDB database, detailed information are stored at the ComplementaryData/physiology/biomassComposition_Cofactor_Ion.tsv
  • Ions transport and exchange reactions were also added into the model
  • All functions related to biomass change were updated

I hereby confirm that I have:

  • Tested my code with all requirements for running the model
  • Selected devel as a target branch (top left drop-down menu)
  • If needed, asked first in the Gitter chat room about this PR

* upload new biomass composition in physiology/biomassCompsition_Cofactor_Ion.tsv
* upload ion related exchange and transport rxns
* update all functions related to the change of new biomass
* upload the function of AddCofactorIon.m
run scaleBiomass will update the model with new biomass composition.
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@BenjaSanchez BenjaSanchez left a comment

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@feiranl below some comments, most of them are for complying with style or errors in the code due to added paths in your Matlab session. Note that as this is a rather larger update, it will be merged to devel after the next yeast 8.3.2 release, so this will go into yeast 8.3.3.

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ComplementaryData/modelCuration/Biomass_newRxnProp.tsv Outdated Show resolved Hide resolved
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* update coefficients for NADH/NADP/NADPH/NAD
* change one rxn name to keep consistency
* fix the cd problem in the function
* fix a bug for rerun the function
rerun the function ScaleBiomass
* update the confidence score to be 2 for those rxns which have GPRs
* update coefficients for NAD/NADH/NADP/NADPH
corret the reference for 9 ions
delete unused variables
@BenjaSanchez BenjaSanchez added the standby work somewhere else is needed before advancing label Nov 8, 2018
@BenjaSanchez BenjaSanchez added wip work in progress and removed standby work somewhere else is needed before advancing labels Nov 8, 2018
@BenjaSanchez BenjaSanchez deleted the NewBiomass branch November 26, 2018 17:28
@BenjaSanchez BenjaSanchez mentioned this pull request Nov 26, 2018
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BenjaSanchez added a commit that referenced this pull request Nov 26, 2018
PR #174 included "cofactor" & "ion" pseudo-metabolites, so addSBOterms.m should be modified accordingly
@BenjaSanchez BenjaSanchez mentioned this pull request Nov 26, 2018
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@BenjaSanchez BenjaSanchez removed the wip work in progress label Dec 3, 2018
@BenjaSanchez BenjaSanchez mentioned this pull request Dec 4, 2018
@feiranl feiranl mentioned this pull request Dec 4, 2018
3 tasks
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4 participants